PI: Willem Mulder, Ph.D.
Professor of Radiology, ISMMS
Professor of Precision Medicine, TU/e
Director, Nanomedicine Program
I obtained an M.Sc. in Chemistry from the Utrecht University (2001) and a Ph.D. in Biomedical Engineering from the Eindhoven University of Technology (2006).
In 2006, directly after my recruitment to Icahn School of Medicine at Mount Sinai (ISMMS) in New York, I founded the Nanomedicine lab, one of four programs within Sinai’s Biomedical Engineering and Imaging Institute. Since January 2012, I distribute my research activities between ISMMS and the Netherlands, first at the AMC in Amsterdam and since 2018 at the Eindhoven University of Technology. This has been a successful setup, allowing fluid exchange of resources, knowhow and personnel between both places.
My research focuses on precision imaging and targeted immunotherapy in cardiovascular disease, cancer and transplantation. I have established library technology, encompassing nanomaterials derived from natural lipoproteins (nanobiologics), that allows meticulously designing targeted immunotherapies. When appropriately designed, such nanobiologics can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics.